Down syndrome is a genetic condition that occurs in one in every 691 births. It is the most frequently occurring chromosomal condition and is found in people of all races and economic levels. National Down Syndrome Society (NDSS) and National Down Syndrome Congress (NDSC) are examples of organisations working for the acceptance and inclusion of people with Down syndrome.

There is a need for development of such societiess and organisations across Pakistan where all people with Down syndrome have the opportunity to enhance their quality of life, realize their life aspirations, and become valued members of welcoming communities.

Pakistan Down Syndrome Association (PDSA) was established in 2009. the purpose of this DPO was to raise awareness about rights of Down Syndrome children in Pakistan. Many people in Pakistan are unaware of Down Syndrome and the ones who are aware and have Down Syndrome children have hidden them at homes.

PDSA is committed to make the people of this country aware about Down Syndrome Children and promote the rights of these children.